User blog comment:Rozh/Surface-to-Orbit Artillery/@comment-379205-20110320194330

I see no reason why a surface to orbit MAC wouldn't work. In order to solve the problem of mobility, I suspect one might be able to place a small anti-ship Gauss Cannon on an Elephant chassis. Alternatively, one could mount one, perhaps two, depending on size, large Gauss Weapons on a "wet" naval vessel.

I would also expect that heavy Gauss cannon-based anti-spacecraft weaponry would be augmented by missile-based anti-spacecraft systems, both nuclear and conventional, and possibly LASER-based systems in the post-HCW era.