User:RelentlessRecusant/RO-28-1675

RO-28-1675 is a chiral small-molecule specific allosteric activator of glucokinase (hexokinase IV). It was originally synthesized and characterized by Grimsby et. al in 2003 by a collaboration between Hoffmann-La Roche Inc., the Department of Biochemistry and Diabetes Center at the University of Pennsylvania School of Medicine, and the Department of Molecular Physiology and Biophysics at Vanderbilt University.