User:RelentlessRecusant/RU-486



RU-486, IUPAC name (11R,13S,17S)-11-(4-(dimethylamino)phenyl)-17-hydroxy-13-methyl-17-(prop-1-ynyl)-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, is a small-molecule chemical inhibitor of the glucocorticoid receptor (Nr3c1) and the progsterone receptor (Nr3c3), with a dissociation constant of KD = 0.4 nM for the glucocorticoid receptor.

It was originally synthesized and characterized by the pharmaceutical company Roussel Uclaf in 1980 at Romainville, France.